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Definition of LINKAGE GROUP
: a set of linked genes at different loci on the same chromosome
First Known Use of LINKAGE GROUP
Medical Definition of LINKAGE GROUP
: a set of genes at different loci on the same chromosome that except for crossing-over tend to act as a single pair of genes in meiosis instead of undergoing independent assortment
All the genes on a single chromosome. They are inherited as a group; during cell division they act and move as a unit rather than independently. Variations in linkage groups can occur if a chromosome breaks, and the sections join with the partner chromosome if it has broken in the same places. This exchange of genes between chromosomes, called crossing-over, usually occurs during meiosis. Sex linkage is the tendency of a characteristic to be linked to one sex; sex-linked traits in humans include red-green colour blindness and hemophilia.