2
: an abnormal change in structure of an organ or part due to injury or disease
especially
: one that is circumscribed (see circumscribe sense 1) and well-defined
Examples of lesion in a Sentence
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Asthma attacks, severe headaches and lesions on her arms and legs painted a mysterious picture for doctors, some of whom suggested the pain was all in her head.
—
Sophie Dodd, PEOPLE, 9 Nov. 2025
White matter lesions occur when the white matter (the brain area consisting of communicating nerve cells) is deprived of oxygen due to poor blood flow, resulting in brain tissue damage and shrinkage (atrophy).
—Colleen Doherty, Verywell Health, 6 Nov. 2025
Mice given IC7Fc had around 84% smaller atherosclerotic lesions than controls.
—New Atlas, 3 Nov. 2025
The robot accurately reconstructed the folds’ geometry, replicating real tissue defects caused by lesion removal or partial reconstruction.
—Aamir Khollam, Interesting Engineering, 29 Oct. 2025
See All Example Sentences for lesion
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Sophie Dodd, PEOPLE, 9 Nov. 2025
White matter lesions occur when the white matter (the brain area consisting of communicating nerve cells) is deprived of oxygen due to poor blood flow, resulting in brain tissue damage and shrinkage (atrophy).
—Colleen Doherty, Verywell Health, 6 Nov. 2025
Mice given IC7Fc had around 84% smaller atherosclerotic lesions than controls.
—New Atlas, 3 Nov. 2025
The robot accurately reconstructed the folds’ geometry, replicating real tissue defects caused by lesion removal or partial reconstruction.
—Aamir Khollam, Interesting Engineering, 29 Oct. 2025
See All Example Sentences for lesion
Cite this Entry
“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 13 Nov. 2025.
Copy CitationKids Definition
lesion
noun
le·sion
ˈlē-zhən 
: a change in the structure of a bodily organ or part due to injury or disease
especially
: an injured or diseased spot or area clearly marked off from healthy tissue around it
Medical Definition
Legal Definition
lesion
noun
le·sion
ˈlē-zhən
in the civil law of Louisiana
: loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)
called also lesion beyond moiety
compare unjust enrichmentEtymology
Anglo-French, damage, injury, from Latin laesio, from laedere to injure
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