Definition of gyrase
: a bacterial enzyme that catalyzes the breaking and rejoining of bonds linking adjacent nucleotides in circular DNA to generate supercoiled DNA helices
Origin and Etymology of gyrase
gyr- + -ase
First Known Use: 1976
Rhymes with gyrase
abase, airspace, Alsace, ambsace, apace, backspace, best-case, biface, birthplace, blackface, boldface, bookcase, bootlace, braincase, briefcase, clubface, crankcase, cyclase, debase, deface, disgrace, displace, dogface, doughface, efface, embrace, emplace, encase, enchase, enlace, erase, euclase, firebase, fireplace, footpace, footrace, foreface, freebase, half-space, hard case, headspace, hydrase, Jerez, kinase, lactase, lightface, lipase, lyase, maltase, manes, millrace, milreis, misplace, mutase, notecase, null-space, nutcase, outface, outpace, outrace, paleface, postface, Quilmes, replace, scapegrace, shoelace, showcase, showplace, slipcase, smearcase, someplace, staircase, subbase, subspace, suitcase, tailrace, tenace, typeface, ukase, unbrace, unlace, watchcase, wheelbase, whey-face, whiteface, workplace, worst-case
Medical Definition of gyrase
: a bacterial enzyme that is a topoisomerase which catalyzes the ATP-dependent breaking and rejoining of double-strands in circular DNA to generate negative supercoils that twist in the opposite direction as the turns in the original helices ◆The supercoils introduced by the bacterial gyrase help to relieve the torsional stress in the circular DNA strands that is a consequence of the unwinding of the DNA during replication.
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Medical Dictionary: Definition of gyrase
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