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gyrase

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noun gyr·ase \ˈjī-ˌrās\

Definition of gyrase

  1. :  a bacterial enzyme that catalyzes the breaking and rejoining of bonds linking adjacent nucleotides in circular DNA to generate supercoiled DNA helices



Origin and Etymology of gyrase

gyr- + -ase


First Known Use: 1976


Medical Dictionary

gyrase

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noun gy·rase \ˈjī-ˌrās, -ˌrāz\

Medical Definition of gyrase

  1. :  a bacterial enzyme that is a topoisomerase which catalyzes the ATP-dependent breaking and rejoining of double-strands in circular DNA to generate negative supercoils that twist in the opposite direction as the turns in the original helices The supercoils introduced by the bacterial gyrase help to relieve the torsional stress in the circular DNA strands that is a consequence of the unwinding of the DNA during replication.




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