topoisomerase
topo·isom·er·ase
noun \ˌtō-pō-ī-ˈsä-mə-ˌrās, -ˌrāz\Definition of TOPOISOMERASE
: any of a class of enzymes that reduce supercoiling in DNA by breaking and rejoining one or both strands of the DNA molecule
Origin of TOPOISOMERASE
top- + isomerase
First Known Use: 1980
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