Definition of graafian follicle
: a mature liquid-filled cavity in a mammalian ovary that ruptures during ovulation to release an egg
Origin of graafian follicle
Regnier de Graaf †1673 Dutch anatomist
First Known Use: 1883
Medical Definition of graafian follicle
: a mature follicle in a mammalian ovary that contains a liquid-filled cavity and that ruptures during ovulation to release an egg—called also vesicular ovarian follicle
Biographical Note for graafian follicle
de Graaf \də-ˈgräf\play , Reinier (1641–1673), Dutch physician and anatomist. De Graaf is regarded as one of the creators of experimental physiology. In 1672 he produced a treatise on the female reproductive organs that is considered one of the seminal works of biology. De Graaf demonstrated ovulation anatomically, pathologically, and experimentally. The treatise contains the description of the structures now known in English as the graafian follicles. The Swiss anatomist Albrecht von Haller (1708–1777) named them after de Graaf. In 1827 the German embryologist Karl Ernst von Baer (1792–1876) discovered that although the graafian follicles contain the eggs from which organisms develop, they are not the eggs themselves.
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