gangrene


1gan·grene

noun \ˈgaŋ-ˌgrēn, gaŋ-ˈ, ˈgan-ˌ, gan-ˈ\

medical : the decay of flesh that occurs in a part of the body that no longer has blood flowing to it

Full Definition of GANGRENE

1
:  local death of soft tissues due to loss of blood supply
2
:  pervasive decay or corruption :  rot <moral gangrene>
gan·gre·nous \ˈgaŋ-grə-nəs\ adjective

Examples of GANGRENE

  1. When gangrene set in, the soldier's leg had to be amputated.

Origin of GANGRENE

Latin gangraena, from Greek gangraina; akin to Greek gran to gnaw
First Known Use: 1543

2gangrene

verb
gan·grenedgan·gren·ing

Definition of GANGRENE

transitive verb
:  to make gangrenous
intransitive verb
:  to become gangrenous

First Known Use of GANGRENE

1607

gangrene

noun    (Concise Encyclopedia)

Localized soft-tissue death (necrosis) from prolonged blood-supply blockage. It can occur in atherosclerosis, diabetes mellitus, or decubitus ulcer, and after severe burns or frostbite. In dry gangrene, gradual blood-supply decrease turns the part discoloured and cold, then dark and dry. Treatment requires improving blood flow. Moist gangrene comes from a sudden blood-supply cutoff. Bacterial infection causes swelling, discoloration, and then a foul smell. Along with antibiotics, tissue removal may be needed to prevent spread, which can be fatal. A more virulent form, gas gangrene, is named for gas bubbles under the skin produced by a highly lethal toxin from clostridium bacteria. The wound oozes brownish, smelly pus. Infection spreads rapidly, causing death. All dead and diseased tissue must be removed and antibiotics given; an antitoxin can also be used.

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