epigenetic

adjective

epi·​ge·​net·​ic ˌe-pə-jə-ˈne-tik How to pronounce epigenetic (audio)
1
a
: of, relating to, or produced by the chain of developmental processes in epigenesis that lead from genotype to phenotype after the initial action of the genes
b
: relating to, being, or involving changes in gene function that do not involve changes in DNA sequence
epigenetic inheritance
2
of a deposit or structure : formed after the laying down of the enclosing rock
epigenetically adverb

Examples of epigenetic in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
That money alone will insulate you from the impact of epigenetic stress responses. Rahkim Sabree, Forbes.com, 5 Aug. 2025 Khatib, of the University of Wisconsin-Madison, said epigenetic changes might be reversible but would depend on significant improvements in a person's environment and overall living conditions. Juliana Kim, NPR, 29 July 2025 There, enzymes break down the metabolites into epigenetic marks known as acetyl groups and place them on histones to activate one set of genes. Viviane Callier, Quanta Magazine, 21 Mar. 2025 After analyzing participants’ DNA with epigenetic clocks, Bischoff-Ferrari and her colleagues found that omega-3 fatty acids actually slackened aging at the biological level, regardless of participants’ body mass index (BMI), age, and gender. Brian Mastroianni, Health, 12 Mar. 2025 See All Example Sentences for epigenetic

Word History

Etymology

epi- + genetic, after epigenesis

First Known Use

1883, in the meaning defined at sense 1a

Time Traveler
The first known use of epigenetic was in 1883

Browse Nearby Words

Cite this Entry

“Epigenetic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/epigenetic. Accessed 20 Aug. 2025.

Medical Definition

epigenetic

adjective
epi·​ge·​net·​ic -jə-ˈnet-ik How to pronounce epigenetic (audio)
1
: of, relating to, or produced by epigenesis
the epigenetic nature of vertebrate development
2
: relating to, being, or involving a modification in gene expression that is independent of the DNA sequence of a gene
epigenetic carcinogenesis
epigenetic inheritance
Methylation is one of many epigenetic signals—chemical changes to DNA and its associated proteins—that modify gene activity without altering the genetic information itself.Tina Hesman Saey, Science News
epigenetically adverb
Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!