transcription factor
noun
: any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription
Examples of transcription factor in a Sentence
Recent Examples on the Web
As with other species, the scientists reprogrammed the elephant cells by exposing them to a series of different chemicals and then adding proteins called transcription factors that turn on particular genes to change how the cells functions.
—
Matt Reynolds, WIRED, 6 Mar. 2024
Enhancers bind many transcription factors to produce that crowding.
—Philip Ball, Quanta Magazine, 14 Feb. 2024
For example, alcohol can cause an alternative form of a gene to be expressed in the memory circuits in flies and people, resulting in changes in dopamine receptors and transcription factors involved in reward signaling and neuronal function.
—Karla Kaun, Discover Magazine, 26 Jan. 2024
Surprising flexibility in a conserved Hox transcription factor over 550 million years of evolution.
—Discover Magazine, 20 Nov. 2019
These messenger molecules go on to act as the blueprints for protein production, so preventing a transcription factor from working can cause all sorts of problems.
—Veronique Greenwood, Discover Magazine, 31 Oct. 2011
Using the gene-editing technology CRISPR in Toxoplasma, the researchers began systematically disabling the genes for proteins known as AP2 transcription factors, which influence gene activity during the parasite’s development.
—Bycatherine Offord, science.org, 31 Mar. 2023
The Church lab’s key discovery was identifying a pair of proteins — known as transcription factors — that reprogram pluripotent stem cells into ovary building blocks in just five days.
—Ryan Cross, BostonGlobe.com, 21 Mar. 2023
For example, one of the transcription factors, which regulate overall gene expression, that was most significantly upregulated is CUX2.
—Angus Chen, STAT, 8 Mar. 2023
Matt Reynolds, WIRED, 6 Mar. 2024
Enhancers bind many transcription factors to produce that crowding.
—Philip Ball, Quanta Magazine, 14 Feb. 2024
For example, alcohol can cause an alternative form of a gene to be expressed in the memory circuits in flies and people, resulting in changes in dopamine receptors and transcription factors involved in reward signaling and neuronal function.
—Karla Kaun, Discover Magazine, 26 Jan. 2024
Surprising flexibility in a conserved Hox transcription factor over 550 million years of evolution.
—Discover Magazine, 20 Nov. 2019
These messenger molecules go on to act as the blueprints for protein production, so preventing a transcription factor from working can cause all sorts of problems.
—Veronique Greenwood, Discover Magazine, 31 Oct. 2011
Using the gene-editing technology CRISPR in Toxoplasma, the researchers began systematically disabling the genes for proteins known as AP2 transcription factors, which influence gene activity during the parasite’s development.
—Bycatherine Offord, science.org, 31 Mar. 2023
The Church lab’s key discovery was identifying a pair of proteins — known as transcription factors — that reprogram pluripotent stem cells into ovary building blocks in just five days.
—Ryan Cross, BostonGlobe.com, 21 Mar. 2023
For example, one of the transcription factors, which regulate overall gene expression, that was most significantly upregulated is CUX2.
—Angus Chen, STAT, 8 Mar. 2023
These examples are programmatically compiled from various online sources to illustrate current usage of the word 'transcription factor.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
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“Transcription factor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/transcription%20factor. Accessed 25 Apr. 2024.
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