tis·​sue ˈti-(ˌ)shü How to pronounce tissue (audio)
 chiefly British  ˈtis-(ˌ)yü
: a piece of soft absorbent tissue paper used especially as a handkerchief or for removing cosmetics
: an aggregate of cells usually of a particular kind together with their intercellular substance that form one of the structural materials of a plant or an animal
: a fine lightweight often sheer fabric
: mesh, network, web
a tissue of lies
tissuey adjective

Example Sentences

She wiped her nose with a tissue. a sample of brain tissue The drug can damage the body's tissues. a box wrapped in tissue
Recent Examples on the Web Muscle tissue is composed of roughly 12 different cell types including stem cells, satellite cells, macrophages, and more. Monique Brouillette, Popular Mechanics, 21 Feb. 2023 The percussion technology is effective at reaching deep into the muscle tissue, providing a thorough and invigorating massage. Lauren Levy, Health, 21 Feb. 2023 That’s because testosterone activates the androgen receptors in muscle tissue to stimulate growth. Alexa Tucker, Men's Health, 12 Feb. 2023 Introducing PerfectAmino Electrolytes - a silky smooth and mouth-watering electrolyte drink fortified with PerfectAmino to reconstruct muscle tissue, boost stamina, and give you the hydration advantage. Amber Smith, Discover Magazine, 8 Feb. 2023 Rhabdomyolysis, which can damage the heart and kidneys, occurs when damaged muscle tissue releases proteins and electrolytes into the blood, according to the CDC. CBS News, 7 Jan. 2023 Next, Trenorol contains ingredients that help your muscle tissue retain more nitrogen. Dallas News, 22 Dec. 2022 Rhabdomyolysis is a rare condition in which skeletal muscle tissue breaks down from intense physical exertion and releases proteins and electrolytes (such as potassium) into the bloodstream at a toxic level. Brian Metzler, Outside Online, 19 Dec. 2022 Trinajstic and her team had previously discovered mineralized muscle tissue in these same placoderm fossils. Stephanie Pappas, Scientific American, 15 Sep. 2022 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'tissue.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


Middle English tysshewe, tyssew, a rich fabric, from Anglo-French tissue, from past participle of tistre to weave, from Latin texere — more at technical

First Known Use

1563, in the meaning defined at sense 3a

Time Traveler
The first known use of tissue was in 1563

Dictionary Entries Near tissue

Cite this Entry

“Tissue.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/tissue. Accessed 30 Mar. 2023.

Kids Definition


tis·​sue ˈtish-ü How to pronounce tissue (audio)
: a fine lightweight fabric
: a piece of soft absorbent paper
: a mass or layer of cells usually of one kind together with the uniting or enclosing substance around and between them that form the basic structural materials of a plant or an animal compare connective tissue

Medical Definition


ˈtish-(ˌ)ü, ˈtish-ə(-w), chiefly British ˈtis-(ˌ)yü
: an aggregate of cells usually of a particular kind together with their intercellular substance that form one of the structural materials of a plant or an animal and that in animals include connective tissue, epithelium, muscle tissue, and nerve tissue
Last Updated: - Updated example sentences
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