The pancreas secretes a substance called insulin.
The floor was covered with a white, powdery substance that turned out to be flour.
heroin and other illegal substances
He had a history of substance abuse.
When has he ever said anything of substance?
The results of the study give substance to their theory.
the substance of my argument See More
Recent Examples on the WebThe hangar first went up in flames last week, releasing asbestos and other toxic substances into the air.—Ryan Fonseca, Los Angeles Times, 14 Nov. 2023 Since then, his fear has given way to fascination with the substance.—Sarah Scoles, Scientific American, 14 Nov. 2023 Divorce is allowed only under certain circumstances including adultery, abandonment, physical or substance abuse, or the commission of a felony.—Annie Karni, New York Times, 12 Nov. 2023 In January 2023, Gov. Janet Mills proposed $94 million to support mental health and substance use disorder services, including funds to reimburse MaineCare, Maine's version of Medicaid, according to local ABC News affiliate WMTW.—Mary Kekatos, ABC News, 10 Nov. 2023 Its potential, however, is immense: Roughly 46 million Americans met the criteria for a substance use disorder as of 2021, according to the White House.—Lev Facher, STAT, 9 Nov. 2023 The substance was identified using preliminary field tests, not more rigorous lab tests at FBI facilities, the official said.—CBS News, 9 Nov. 2023 The gathering proved to be a meta affair, more about process than substance.—Paul Elie, The New Yorker, 8 Nov. 2023 During his life, the actor also transformed his own Malibu home into Perry House, a men’s sober living facility for those struggling with substance abuse.—Daniel Kreps, Rolling Stone, 3 Nov. 2023 See More
These examples are programmatically compiled from various online sources to illustrate current usage of the word 'substance.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
Middle English, from Anglo-French, from Latin substantia, from substant-, substans, present participle of substare to stand under, from sub- + stare to stand — more at stand