progesterone

noun

pro·​ges·​ter·​one prō-ˈje-stə-ˌrōn How to pronounce progesterone (audio)
: a female steroid sex hormone C21H30O2 that is secreted by the corpus luteum to prepare the endometrium for implantation and later by the placenta during pregnancy to prevent rejection of the developing embryo or fetus
also : a synthetic steroid resembling progesterone in action

Examples of progesterone in a Sentence

Recent Examples on the Web Fibroids typically resolve with the onset of menopause as estrogen and progesterone production wanes. Rachel Murphy, Verywell Health, 21 May 2024 The body's production of estrogen and progesterone (hormones made by the ovaries) varies during perimenopause. Korin Miller, Health, 19 May 2024 First, the person takes mifepristone which blocks progesterone, then up to 48 hours later, the person takes misoprostol which expels the pregnancy tissue over the course of 12 to 24 hours, Yale Medicine says. Irene Wright, Miami Herald, 13 May 2024 For both menstrual mood disorders, symptoms surface during the luteal phase, when the hormones estrogen and progesterone increase in the body to thicken the lining of the uterus, then decline if there’s no fertilized egg present. Angela Roberts, Baltimore Sun, 26 Feb. 2024 Most researchers believe that PMS occurs after ovulation due to a dramatic fall in estrogen and progesterone levels in people who are not pregnant.3 Not every person who menstruates will experience PMS symptoms, but most people do.3 Some people may only feel mild effects of PMS. Elizabeth Pratt, Health, 12 May 2024 The Depo-Provera contraceptive works by injecting a very small amount of progesterone into the body in order to prevent pregnancy, and shots are typically administered every 11 to 13 weeks. Lily Carey, Discover Magazine, 18 Apr. 2024 By the end of the decade, 15 million women were on estrogen therapy, with or without progesterone, to treat their menopause symptoms. Rachel E. Gross, The Atlantic, 17 Apr. 2024 Mifepristone blocks a hormone called progesterone, which helps the body maintain the inside of the uterus so a pregnancy can continue. Jen Christensen, CNN, 25 Mar. 2024

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'progesterone.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

blend of progestin and luteosterone (borrowed from German Luteosteron, from luteo- luteo- + -steron -sterone), both earlier names for progesterone

Note: The name resulted from a compromise between researchers associated with the earlier names, the American gynecologist Willard M. Allen and embryologist George Washington Corner, and the German biochemists Adolph Butenandt and Karl Heinrich Slotta. See W. M. Allen, A. Butenandt, G. W. Corner, and K. H. Slotta, "Nomenclature of Corpus Luteum Hormone," Nature, vol. 136, number 303 (September 1, 1935), p. 303.

First Known Use

1935, in the meaning defined above

Time Traveler
The first known use of progesterone was in 1935

Dictionary Entries Near progesterone

Cite this Entry

“Progesterone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/progesterone. Accessed 28 May. 2024.

Kids Definition

progesterone

noun
pro·​ges·​ter·​one prō-ˈjes-tə-ˌrōn How to pronounce progesterone (audio)
: a hormone that is produced by the corpus luteum and causes the uterus to change so that it provides a suitable environment for a fertilized egg

Medical Definition

progesterone

noun
pro·​ges·​ter·​one prō-ˈjes-tə-ˌrōn How to pronounce progesterone (audio)
: a female steroid sex hormone C21H30O2 that is secreted by the corpus luteum to prepare the endometrium for implantation and later by the placenta during pregnancy to prevent rejection of the developing embryo or fetus
also : a synthetic steroid resembling progesterone in action

More from Merriam-Webster on progesterone

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