mul·​ti·​va·​lent ˌməl-tē-ˈvā-lənt How to pronounce multivalent (audio) -ˌtī- How to pronounce multivalent (audio)
especially in sense 3
ˌməl-ˈti-və- How to pronounce multivalent (audio)
: represented more than twice in the somatic chromosome number
multivalent chromosomes
: having many values, meanings, or appeals
multivalent noun

Example Sentences

Recent Examples on the Web In its very unconventionality as well as its focus on today’s youth, Social Sculpture is a living testament to the late multivalent talent. Janelle Zara, ELLE Decor, 5 July 2022 In remembering his life and times and attempting to parse the man from the myth, audiences come closer to understanding the multivalent meanings of American culture. Grant Wong, Smithsonian Magazine, 23 June 2022 But Moderna touted the findings as evidence that bivalent or multivalent vaccines—those that target two or more versions of the virus in a single shot—are the way forward for COVID-19 boosters. Beth Mole, Ars Technica, 21 Apr. 2022 Deploying a vaccine that targets more than one variant, also known as a multivalent vaccine, could provide broader protection than the existing vaccines. NBC News, 6 Apr. 2022 Hoge also said the company is working on a multivalent vaccine dose that would target four variants, including omicron. Beth Mole, Ars Technica, 2 Dec. 2021 The company is taking a three-pronged approach, studying how a higher-dose booster holds up against omicron, as well as testing two other multivalent boosters and one that's specifically created to address the omicron mutations. Kristen Jordan Shamus, Detroit Free Press, 9 Dec. 2021 Writer-director Leslie Harris uses Brooklyn in all its multivalent Blackness as a backdrop for the story of Chantal (Ariyan A. Johnson), a high-school junior whose strength of characterization is rooted in her normalcy. Alison Willmore, Vulture, 6 Dec. 2021 On November 26, Moderna released a three-pronged plan to address Omicron that includes testing higher doses, developing multivalent vaccines, and making an Omicron-specific vaccine. Yasmin Tayag, Fortune, 2 Dec. 2021 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'multivalent.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History


International Scientific Vocabulary

First Known Use

1863, in the meaning defined at sense 1

Time Traveler
The first known use of multivalent was in 1863

Dictionary Entries Near multivalent

Cite this Entry

“Multivalent.” Dictionary, Merriam-Webster, Accessed 1 Dec. 2022.

Medical Definition

multivalent 1 of 2


mul·​ti·​va·​lent ˌməl-ti-ˈvā-lənt How to pronounce multivalent (audio) -ˌtī- How to pronounce multivalent (audio)
: represented more than twice in the somatic chromosome number
multivalent chromosomes


2 of 2


: a multivalent group of chromosomes
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