Definition of metastasis
1a
: change of position, state, or form
b
: the spread of a disease-producing agency (such as cancer cells) from the initial or primary site of disease to another part of the body
metastasis of breast cancer to bone — Medical Physics
also
: the process by which such spreading occurs
2
: a secondary malignant (see malignant sense 1) tumor resulting from metastasis
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Merriam-Webster unabridged
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Time Traveler for metastasis
The first known use of metastasis was in 1663
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