insulin-like growth factor

noun

in·​su·​lin-like growth factor ˈin(t)-s(ə-)lən-ˈlīk- How to pronounce insulin-like growth factor (audio)
: either of two polypeptides structurally similar to insulin that are secreted either during fetal development or during childhood and that mediate growth hormone activity

Examples of insulin-like growth factor in a Sentence

Recent Examples on the Web
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This affordable serum contains synthetic versions of epidermal, transforming, and insulin-like growth factors (EGF, TGF, and IGF, respectively) made of peptides to help renew skin. Emily Orofino, Vogue, 6 May 2025 People who take a GLP-1 medication also tend to have elevated levels of insulin-like growth factor 1 (IGF-1), a growth hormone that helps control sebum production. Claire Bugos, Verywell Health, 10 Apr. 2025 During childhood, hormones—including thyroid hormones, human growth hormone (HGH), and insulin-like growth factor 1—play a major role in healthy growth and development. Laura Dorwart, Verywell Health, 2 Jan. 2025 These peptides, in turn, activate the insulin-like growth factor 1 (IGF-1) signaling pathway in NSCs and triggers their reactivation. New Atlas, 15 Aug. 2024 Researchers are unsure exactly why dairy causes acne, but some evidence suggests that milk raises insulin-like growth factor 1 (IGF-1) levels, which increases sebum (oil) production. Kathleen Felton, Health, 11 Sep. 2023 Laron syndrome results from a mutation in the gene that codes for growth hormone receptor (GHR), a protein that binds with the human growth hormone and ultimately results in the production of the insulin-like growth factor 1 (IGF1), causing cells to grow and divide. Andrew Moseman, Discover Magazine, 17 Feb. 2011 In 1956 Daughaday discovered the hormone now called insulin-like growth factor 1, or IGF-1. Gary Taubes, Discover Magazine, 26 Mar. 2013 As animals grow, two proteins play a major role: insulin and insulin-like growth factor (known as IGF). Carl Zimmer, Discover Magazine, 26 July 2012

Word History

First Known Use

1976, in the meaning defined above

Time Traveler
The first known use of insulin-like growth factor was in 1976

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Cite this Entry

“Insulin-like growth factor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin-like%20growth%20factor. Accessed 11 May. 2025.

Medical Definition

insulin-like growth factor

noun
in·​su·​lin-like growth factor ˌin(t)-s(ə-)lən-ˌlīk- How to pronounce insulin-like growth factor (audio)
: either of two polypeptides structurally similar to insulin that are secreted either during fetal development or during childhood and that mediate growth hormone activity
Last Updated: - Updated example sentences
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