immune system

noun

: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells, and antibodies

Examples of immune system in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The product could cause adverse health consequences—including life-threatening infections—in people with weakened immune systems. Jenna Anderson, Health, 12 Dec. 2025 Key Takeaways Elderberry may help support your immune system and shorten the duration of colds or ease symptoms. Morgan Pearson, Verywell Health, 12 Dec. 2025 Alcohol impairs the immune system through several mechanisms, said Ednie, including disrupting communication between immune cells and damaging the gut barrier — both of which can trigger widespread inflammation. Andrea Margolis, FOXNews.com, 11 Dec. 2025 Unlike lactose intolerance, which is a digestive issue, milk allergy involves the immune system mistakenly identifying milk proteins as harmful and triggering an allergic response. Associate News Editor, MSNBC Newsweek, 11 Dec. 2025 See All Example Sentences for immune system

Word History

First Known Use

1899, in the meaning defined above

Time Traveler
The first known use of immune system was in 1899

Browse Nearby Words

Cite this Entry

“Immune system.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/immune%20system. Accessed 19 Dec. 2025.

Kids Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, lymphocytes, and antibodies

Medical Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), lymphocytes including the B cells and T cells, and antibodies

More from Merriam-Webster on immune system

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