immune

adjective

im·​mune i-ˈmyün 

1

: not susceptible or responsive

immune to all pleas

especially : having a high degree of resistance to a disease

immune to diphtheria

2

a

: produced by, involved in, or concerned with immunity or an immune response

immune agglutinins

immune globulins

b

: having or producing antibodies or lymphocytes capable of reacting with a specific antigen

an immune serum

3

a

: marked by protection

some criminal leaders are immune from arrest

b

: free, exempt

immune from further taxation

immune noun

Frequently Asked Questions

Is it 'immune to' or 'immune from'?

In most cases, if you are immune to something, it has no effect on you—for example, you might be immune to a disease or to criticism. If you are immune from something, it cannot reach you—for example, you might be immune from prosecution in a plea bargain.

What is the immune system?

The immune system is what protects your body from diseases and infections. It's the bodily system that produces the immune response to defend your body from foreign substances, cells, and tissues. The immune system includes various parts of the body including the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (such as those in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells, and antibodies.

What is herd immunity?

The term herd immunity refers to a reduction in the likelihood of someone catching a specific infectious disease because a significant proportion of the people in that person's community are immune to it. If you are less likely to come in contact with an infectious person, you're less likely to get infected yourself. The people in a community can be immune to a particular disease especially through previous exposure or vaccination.

Examples of immune in a Sentence

Recent Examples on the Web

This approach often involves a combination of therapies, including systemic anti-inflammatory medications, newer treatments designed to interrupt specific immune pathways and supportive care strategies such as wound management, pain control and lifestyle adjustments. —Lauryn Higgins, Flow Space, 6 May 2026

Griffin will no doubt continue his long-running argument that no city, however dominant, is immune to the consequences of driving away its productive class. —Nick Lichtenberg, Fortune, 6 May 2026

Helps with energy, immune function, mood, and dopamine regulation (Cleveland Clinic). —Ryan Brennan may 6, Fort Worth Star-Telegram, 6 May 2026

Frequent fliers must overcome practical challenges to offset the threats to hydration, sleep, circulation, and immune function posed by extended time in an aircraft cabin. —Anna Giorgi, Verywell Health, 6 May 2026

Word History

Etymology

Middle English, from Latin immunis, from in- + munia services, obligations; akin to Latin munus service — more at mean

First Known Use

15th century, in the meaning defined at sense 3b

Phrases Containing immune

• acquired immune deficiency syndrome
• hyper-immune
• immune-compromised
• immune response
• immune surveillance
• immune system
• intravenous immune globulin

Rhymes for immune

• attune
• baboon
• balloon
• bassoon
• buffoon
• cartoon
• cocoon
• festoon
• gaboon
• harpoon
• impugn
• jejune

Kids Definition

immune

adjective

im·​mune im-ˈyün 

1

: exempt entry 1

immune from punishment

2

a

: not influenced by something

immune to persuasion

b

: having a high degree of resistance to an illness or disease

3

: containing or producing antibodies

Medical Definition

immune

1 of 2 adjective

im·​mune im-ˈyün 

1

: not susceptible or responsive

especially : having a high degree of resistance to a disease

immune to diphtheria

2

a

: having or producing antibodies or lymphocytes capable of reacting with a specific antigen

an immune serum

b

: produced by, involved in, or concerned with immunity or an immune response

immune agglutinins

immune

2 of 2 noun

: an immune individual

Legal Definition

immune

adjective

im·​mune i-ˈmyün 

: having immunity : exempt