1
: of superior grade or quality
high-grade bonds
2
a
: being near the upper or most favorable extreme of a specified range
b
: medically serious or life-threatening
a high-grade tumor

Examples of high-grade in a Sentence

Recent Examples on the Web The 257 patients who completed the study all had asymptomatic extracranial high-grade internal carotid artery stenosis — in other words, their carotid arteries were blocked with plaque. Susanne Rust, Los Angeles Times, 7 Mar. 2024 Cameco has been ramping up production at the world’s largest high-grade uranium mine and mill — MacArthur River and Key Lake in the western Canadian province of Saskatchewan — after idling operations between 2018 and 2021 due to weak market conditions. Jacob Lorinc, Fortune, 3 Mar. 2024 About North Shore Uranium The near-term business objectives of North Shore Uranium are to become a major force in exploration for economic uranium deposits at the eastern margin of Saskatchewan's Athabasca Basin, a tier-one jurisdiction for discovering new mineable high-grade uranium deposits. Kansas City Star, 28 Feb. 2024 The set comes with 80 durable, high-grade plastic blocks in a convenient zip-up storage bag. Christine Luff, Parents, 27 Feb. 2024 This sleep mask features high-grade, long-fiber mulberry silk wrapped around plush foam padding. Theresa Holland, Travel + Leisure, 26 Feb. 2024 South32 is drilling in nearby Flux Canyon, for instance, and Risner said an exploratory drill in that canyon recently struck a 7-meter vein of high-grade zinc, with more holes yet to be drilled. Brandon Loomis, The Arizona Republic, 15 Feb. 2024 Winkle’s later-life career change, a story dramatic in its details of risky business, sudden riches and an inauspicious demise, is just one colorful thread in the vast tapestry of the California marijuana black market that supplies much of America with high-grade, illicit pot. Peter Hecht, Sacramento Bee, 21 Feb. 2024 Expect to pay between $400 and $1,000 for mid- to high-grade sets. Laura Daily, Washington Post, 4 Feb. 2024

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'high-grade.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1826, in the meaning defined at sense 1

Time Traveler
The first known use of high-grade was in 1826

Dictionary Entries Near high-grade

Cite this Entry

“High-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/high-grade. Accessed 29 Mar. 2024.

Kids Definition

high-grade

adjective
ˈhī-ˈgrād
: of a better grade or quality

Medical Definition

high-grade

adjective
: being near the upper, most serious, or most life-threatening extreme of a specified range
high-grade gliomas
high-grade cervical dysplasia
compare low-grade

More from Merriam-Webster on high-grade

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!