gene

noun

plural genes
: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

Examples of gene in a Sentence

She inherited a good set of genes from her parents.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
But the really rare mutation Iris has is on a gene that's responsible for mitochondria and mitochondrial disease. Hannah Sacks, PEOPLE, 10 Nov. 2025 The discovery helped open the door to more recent developments such as tinkering with the genetic makeup of living things, treating disease by inserting genes into patients, identifying human remains and criminal suspects from DNA samples, and tracing family trees and ancient human ancestors. Orianna Rosa Royle, Fortune, 9 Nov. 2025 The discovery revealed how genetic information is stored and replicated and created the foundation for modern genetic engineering, disease treatment with genes and DNA identification techniques, according to The Associated Press. Sophia Compton, FOXNews.com, 8 Nov. 2025 People with a nonfunctioning ANGPTL3 gene — which Natarajan says applies to about 1 in 250 people in the US — have lifelong levels of low LDL cholesterol and triglycerides without any apparent negative consequences. Sandee Lamotte, CNN Money, 8 Nov. 2025 See All Example Sentences for gene

Word History

Etymology

German Gen, short for Pangen, from pan- + -gen

First Known Use

1909, in the meaning defined above

Time Traveler
The first known use of gene was in 1909

Cite this Entry

“Gene.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/gene. Accessed 15 Nov. 2025.

Kids Definition

gene

noun
: a part of DNA or sometimes RNA that is usually located on a chromosome and that contains chemical information needed to make a particular protein (as an enzyme) controlling or influencing an inherited bodily trait or activity (as eye color or metabolism) or that influences or controls the activity of another gene or genes

Medical Definition

gene

noun
: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

called also determinant, determiner, factor

More from Merriam-Webster on gene

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