fatal

adjective

fa·​tal ˈfā-tᵊl 

1

a

: causing death

a fatal crash

a fatal disease

a fatal wound

b

: bringing ruin

a fatal attraction to gambling

c

: causing failure

a fatal design flaw

Lack of sufficient support was fatal to his campaign.

2

a

: determining one's fate

… the fatal flaw in this dazzling woman: a total lack of taste.

—Marya Mannes

b

: of or relating to fate

… this science sets a fatal necessity on things …

—Henry Osborn Taylor

c

: resembling fate in proceeding according to a fixed sequence

3

: fateful

a fatal hour

4

obsolete : fated

Synonyms of fatal

• disastrous
• catastrophic
• unfortunate

Choose the Right Synonym for fatal

deadly, mortal, fatal, lethal mean causing or capable of causing death.

deadly applies to an established or very likely cause of death.

a deadly disease

mortal implies that death has occurred or is inevitable.

a mortal wound

fatal stresses the inevitability of what has in fact resulted in death or destruction.

fatal consequences

lethal applies to something that is bound to cause death or exists for the destruction of life.

lethal gas

Examples of fatal in a Sentence

a disease that is often fatal

a chemical that can be fatal to birds

She made a fatal mistake.

Recent Examples on the Web

While some people can clear the infection on their own, the majority are at major risk of developing chronic, potentially fatal conditions like cirrhosis and end-stage liver disease. — Philip A. Chan, STAT, 8 Oct. 2026

Gounaris believes the prospect of losing those things may have pushed him toward a fatal decision. — Greg Wehner, FOXNews.com, 8 Oct. 2026

The provider had been involved in a fatal mistake, the lawsuit alleges, but KCFD delayed a hearing while unsafe practices continued. — Ben Wheeler, Kansas City Star, 8 Oct. 2026

The Illinois State Police is launching an investigation into the fatal ICE shooting of Silverio in 2025. — Laura Rodríguez Presa, Chicago Tribune, 8 Oct. 2026

Word History

Etymology

Middle English, from Latin fatalis, from fatum fate

First Known Use

14th century, in the meaning defined at sense 4

Phrases Containing fatal

• dealt a fatal blow

Rhymes for fatal

• datal
• antenatal
• hiatal
• neonatal
• perinatal
• nonfatal
• postnatal
• prenatal

Kids Definition

fatal

adjective

fa·​tal ˈfāt-ᵊl 

1

: deciding one's fate : fateful

on that fatal day

2

: causing death or ruin

a fatal accident

fatally

-ᵊl-ē

adverb

Medical Definition

fatal

adjective

fa·​tal ˈfāt-ᵊl 

: causing death

a fatal diabetic coma

—Havelock Ellis

fatally

ˈfāt-ᵊl-ē 

adverb

Legal Definition

fatal

adjective

fa·​tal

1

: causing failure of a legal claim or cause of action

a fatal defect in the proceedings

—W. R. LaFave and J. H. Israel

2

: making something (as a contract) invalid or unenforceable

there is a fatal indefiniteness with the result that the agreement is void

—J. D. Calamari and J. M. Perillo

fatally adverb