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annealed; annealing; anneals
1
a
: to heat and then cool (a material, such as steel or glass) usually for softening and making less brittle
also
: to cool slowly usually in a furnace
b
: to cause two complementary strands of nucleic acid (such as DNA or RNA) to join by hydrogen bonding
also
: to induce the binding of a genetic primer (see primer entry 2 sense 3) to a complementary single-stranded nucleic acid by slowly cooling single strands obtained from the heating and separation of double-stranded DNA or RNA
The primers are annealed to the single strands when the local temperature is reduced to between 50 and 65 C. —
Andrew J. DeMello
During PCR, fragments are heated so they will separate into single strands. A short nucleotide sequence called a primer is then annealed to each original template. —
George M. Church
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Merriam-Webster unabridged
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