sirolimus

noun

si·​ro·​li·​mus si-ˈrō-li-məs How to pronounce sirolimus (audio)
: an immunosuppressive drug C51H79NO13 that is a macrocyclic lactone obtained from a soil bacterium of the genus Streptomyces (S. hygroscopicus) and is taken orally especially to prevent rejection of transplanted organs
Sirolimus (also called rapamycin) is a macrolide antibiotic that blocks proliferative responses of lymphocytes to interleukin-2 by inhibiting interleukin-2-mediated signal-transduction events.Manuel Pascual et al., The New England Journal of Medicine

called also rapamycin

Note: Sirolimus is often taken in combination with other immunosuppressive drugs (such as cyclosporine) and is marketed under the trademark Rapamune.

Dictionary Entries Near sirolimus

Cite this Entry

“Sirolimus.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/sirolimus. Accessed 23 Apr. 2024.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!