protease

noun

pro·​te·​ase ˈprō-tē-ˌās How to pronounce protease (audio)
-ˌāz
: any of numerous enzymes that hydrolyze proteins and are classified according to the most prominent functional group (such as serine or cysteine) at the active site

called also proteinase

Examples of protease in a Sentence

Recent Examples on the Web Enzyme supplements such as amylase (for carbohydrates), protease (for proteins), and lipase (for fats) can aid in digestion and reduce symptoms of bloating, gas, and indigestion, especially for individuals with enzyme deficiencies or digestive disorders. Marilyn La Jeunesse, Glamour, 12 Apr. 2024 Raw probiotic & enzyme blend: lipase, protease, aspergillopepsin, beta-glucanase, cellulase, bromelain, phytase, lactase, papain, peptidase, pectinase, hemicellulase, xylanase, [lactobacillus bulgaricus, lactobacillus plantarum] (500 million cfu). Kelsey Kunik, Rd, Health, 25 July 2023 That protein—called a protease—has remained mostly unchanged across variants, Mina added. Kaitlin Sullivan, Health, 29 Sep. 2023 The fungus then uses proteases to digest nematodes that get stuck in its hyphae. Elizabeth Rayne, Ars Technica, 18 Dec. 2023 Digestive Enzymes: Enzymes such as amylase and protease aid in breaking down food particles more efficiently, ensuring better nutrient absorption and reducing the appeal of undigested waste. Amber Smith, Discover Magazine, 5 Aug. 2023 Now, in a study of mice and human samples, a team of scientists has found that S. aureus releases an enzyme called V8 protease onto the skin, which helps activate itch-driving neurons. Margaret Osborne, Smithsonian Magazine, 4 Dec. 2023 The Merck pill, which doesn’t affect protease but instead introduces mutational errors through an enzyme called polymerase, initially showed a 50% reduction in hospitalization and death in high-risk unvaccinated people with mild or moderate COVID-19. Colleen Stinchcombe, SELF, 14 Dec. 2021 The drug works differently from vaccines and monoclonal antibody treatments by targeting a different part of the virus, called proteases. Kaitlin Sullivan, Health, 29 Sep. 2023

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'protease.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

borrowed from French protéase, from protéine protein + -ase -ase

Note: The French term was probably introduced by the Italian microbiologist and philosopher Giovanni Malfitano (1872-1941) in "Sur le protéase de l'Aspergillus niger," Annales de l'Institut Pasteur, tome quatorzième (1900), p. 420. The term protease was used in English without attribution to Malfitano and perhaps coined independently by the British botanist Sydney Howard Vines (1849-1934) in "Proteolytic Enzymes in Plants," Annals of Botany, vol. 17, no. 65 (January, 1903), p. 237.

First Known Use

1903, in the meaning defined above

Time Traveler
The first known use of protease was in 1903

Dictionary Entries Near protease

Cite this Entry

“Protease.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/protease. Accessed 23 Apr. 2024.

Medical Definition

protease

noun
pro·​te·​ase ˈprōt-ē-ˌās, -ˌāz How to pronounce protease (audio)
: any of numerous enzymes that hydrolyze proteins and are classified according to the most prominent functional group (as serine or cysteine) at the active site

called also proteinase

compare peptidase

More from Merriam-Webster on protease

Last Updated: - Updated example sentences
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