paroxetine

noun

par·​ox·​e·​tine pa-ˈräk-sə-ˌtēn 

: a drug C₁₉H₂₀FNO₃ that enhances serotonin activity and is usually administered in the form of its hydrochloride to treat depression

Examples of paroxetine in a Sentence

Recent Examples on the Web

There are also four medications (sertraline, paroxetine, fluoxetine, and venlafaxine) that have a conditional recommendation to treat PTSD. —Laura Baisas, Popular Science, 30 Nov. 2023

For these people, antidepressants such as paroxetine, sertraline and venlafaxine are recommended as alternatives, or as an addition to psychotherapy. —C. Michael White, The Conversation, 8 Nov. 2023

The lead authors are from GlaxoSmithKline, who invented paroxetine. —Neuroskeptic, Discover Magazine, 6 Mar. 2011

Standard doses of fluoxetine (Prozac) and paroxetine (Paxil), two of the biggest-selling SSRI antidepressants, both had a devastating effect on the survival of mammalian nerve cells growing in a dish. —Neuroskeptic, Discover Magazine, 2 May 2010

Psychedelics and trauma Why would one to two psychedelic therapy sessions be more effective than taking daily prescription medications like fluoxetine (Prozac) and paroxetine (Paxil)? Receiving a cancer diagnosis and experiencing adverse effects from treatments can be traumatic. —C. Michael White, Fortune Well, 17 Apr. 2023

One of Noble's patients saw particular success with Brisdelle (paroxetine), an SSRI that’s been FDA-approved to treat hot flashes and night sweats associated with menopause. —Rachel Murphy, Verywell Health, 28 Mar. 2023

Medications like fluoxetine, paroxetine, and escitalopram have shown to delay ejaculation as a side-effect of the drugs, Dr. Kaufman said. —Korin Miller, Health, 23 Mar. 2023

Now a new paper claims to provide a definitive assessment of the safety and efficacy of paroxetine in adults (age 18+). —Neuroskeptic, Discover Magazine, 6 Mar. 2011

Word History

Etymology

perhaps from International Scientific Vocabulary par- (alteration of piperidine) + ox- + methyl + -ine entry 2

First Known Use

1977, in the meaning defined above

Medical Definition

paroxetine

noun

par·​ox·​e·​tine par-ˈäk-sə-ˌtēn 

: a drug that functions as an SSRI and is usually taken orally in the form of its hydrochloride C₁₉H₂₀FNO₃·HCl or mesylate C₁₉H₂₀FNO₃·CH₄O₃S to treat depression, anxiety, panic disorder, and obsessive-compulsive disorder and to relieve symptoms (such as hot flashes) of menopause

Note: Trademarks for paroxetine include Brisdelle, Paxil, and Pexeva.