estradiol

noun

es·​tra·​di·​ol ˌe-strə-ˈdī-ˌȯl How to pronounce estradiol (audio) -ˌōl How to pronounce estradiol (audio)
: a natural estrogenic hormone that is a phenolic alcohol C18H24O2 secreted chiefly by the ovaries, that is the most potent of the naturally occurring estrogens, and that is administered in its natural or semisynthetic esterified form especially to treat menopausal symptoms

Examples of estradiol in a Sentence

Recent Examples on the Web The resultant electrical signal can be wirelessly measured and correlated to estradiol levels via a simple-to-use smartphone app. Andrew Paul, Popular Science, 5 Oct. 2023 The rat hole has been filled with coins and surrounded by offerings, including a shrine, handmade signs, gifts and even estradiol pills, which are estrogen hormones. Kat Tenbarge, NBC News, 24 Jan. 2024 Specifically, the researchers observe that natal male veterans who were diagnosed with gender dysphoria and/or prescribed estrogen or estradiol have almost double the incidence of thyroid cancer compared with other male veterans. Ian Kingsbury, National Review, 9 Jan. 2024 With further optimization, the new estradiol sensor could help users attempting to naturally or in vitro conceive children, as well as aid those necessitating hormone replacement therapies. Andrew Paul, Popular Science, 5 Oct. 2023 Currently, estradiol monitoring requires blood or urine samples collected either in-clinic or at-home. Andrew Paul, Popular Science, 5 Oct. 2023 For example, estradiol is low early in the follicular phase (EFP) and peaks in the late follicular phase (LFP). Alex Hutchinson, Outside Online, 5 Apr. 2023 The resulting inflammation may alter the expression of progesterone and estrogen receptors in endometrial cells: as a result, cells pump out more estradiol, a form of estrogen that fuels growth of lesions, unchecked by progesterone. Jena Pincott, Scientific American, 1 June 2018 This formula also promotes a boost in free testosterone levels while reducing estradiol. Amber Smith, Discover Magazine, 12 June 2023

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'estradiol.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

International Scientific Vocabulary estra- (from estrane parent compound of estradiol, from New Latin estrus + English -ane) + di- + -ol entry 1

First Known Use

1934, in the meaning defined above

Time Traveler
The first known use of estradiol was in 1934

Dictionary Entries Near estradiol

Cite this Entry

“Estradiol.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/estradiol. Accessed 19 Apr. 2024.

Medical Definition

estradiol

noun
es·​tra·​di·​ol ˌes-trə-ˈdī-ˌȯl How to pronounce estradiol (audio) -ˌōl How to pronounce estradiol (audio)
variants or chiefly British oestradiol
: a natural estrogenic hormone that is a phenolic alcohol C18H24O2 secreted chiefly by the ovaries, is the most potent of the naturally occurring estrogens, and is administered in its natural or semisynthetic esterified form especially to treat menopausal symptoms

called also dihydrotheelin

see estrace, estraderm, estring

More from Merriam-Webster on estradiol

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!