Duchenne muscular dystrophy

noun

Du·​chenne muscular dystrophy dü-ˈshen- How to pronounce Duchenne muscular dystrophy (audio)
də-
: a severe progressive X-linked muscular dystrophy of males marked by early childhood onset and absence of the protein dystrophin

called also Duchenne's muscular dystrophy

compare becker muscular dystrophy

Examples of Duchenne muscular dystrophy in a Sentence

Recent Examples on the Web The agency has used a flexible approach in recent years to approve drugs for particularly devastating conditions such as ALS, Alzheimer’s and Duchenne muscular dystrophy, a fatal disease that causes the muscles of young boys to waste away. Daniel Gilbert, Washington Post, 16 Mar. 2024 And here’s the story of a 5-year-old candidate for a gene therapy for Duchenne muscular dystrophy. Stat Staff, STAT, 28 Dec. 2023 These concerns extend to various medical conditions, including ALS, Duchenne muscular dystrophy, cystic fibrosis, and other rare diseases. Jon Hu, STAT, 18 Dec. 2023 In Duchenne, new data bring a familiar debate This week’s news that Sarepta Therapeutics’ gene therapy for Duchenne muscular dystrophy missed its main goal in a pivotal study has drawn diametric reactions. Damian Garde, STAT, 2 Nov. 2023 In the next few weeks, Sarepta Therapeutics will release new data that could change the future of the company and the lives of thousands of patients with Duchenne muscular dystrophy. Jason Mast, STAT, 30 Oct. 2023 Our colleague Jason Mast joins us to explain how the approval of a landmark gene therapy for Duchenne muscular dystrophy set in motion a frantic race to get children treated before their 6th birthdays. Adam Feuerstein, STAT, 17 Aug. 2023 Last month, the group opposed the FDA’s approval of the first gene therapy for Duchenne muscular dystrophy, a $3.2 million one-time treatment from a Cambridge biotech, Sarepta Therapeutics. Robert Weisman, BostonGlobe.com, 31 July 2023 Researchers have found ways to alter or turn off disease-causing genes in leukemia, hemophilia A, spinal muscular atrophy, Duchenne muscular dystrophy, and other diseases. Isabella Cueto, STAT, 10 July 2023

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'Duchenne muscular dystrophy.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

Guillaume Armand Duchenne †1875 French neurologist

First Known Use

1971, in the meaning defined above

Time Traveler
The first known use of Duchenne muscular dystrophy was in 1971

Dictionary Entries Near Duchenne muscular dystrophy

duchan

Duchenne muscular dystrophy

Duchesnea

Cite this Entry

“Duchenne muscular dystrophy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/Duchenne%20muscular%20dystrophy. Accessed 28 Mar. 2024.

Medical Definition

Duchenne muscular dystrophy

noun
variants also Duchenne's muscular dystrophy
: a severe progressive form of muscular dystrophy of males that appears in early childhood, affects the muscles of the legs before those of the arms and the proximal muscles of the limbs before the distal ones, is inherited as an X-linked recessive trait, is characterized by complete absence of the protein dystrophin, and usually has a fatal outcome by age 20
abbreviation DMD
see becker muscular dystrophy
Last Updated: - Updated example sentences
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