deaminase
noun
de·am·i·nase
(ˌ)dē-ˈa-mi-ˌnās 
-ˌnāz
: an enzyme that hydrolyzes amino compounds (such as amino acids) with removal of the amino group
Examples of deaminase in a Sentence
Recent Examples on the Web
Splitting the enzyme, called a deaminase, into two harmless halves kept it from killing cells.
—
Sharon Begley, STAT, 8 July 2020
Crucially, the mutations that had broken these genes could in principle be fixed with an adenine deaminase that worked on DNA.
—The Economist, 26 Oct. 2017
The enzyme needed is an adenine deaminase that works on DNA.
—The Economist, 26 Oct. 2017
Ramus was born with adenosine deaminase deficiency (ADA), a condition also known as bubble boy disease that affects the immune system.
—Paul A. Smith, Milwaukee Journal Sentinel, 27 Oct. 2017
Creating this second base editor was harder than the first because an equivalent to the cytidine deaminase used by Dr Liu, which would be needed to pull it off, does not exist in nature.
—The Economist, 26 Oct. 2017
Getting to the point of mutations Base editors borrow from CRISPR's components—guide RNAs (gRNAs) and Cas9 or other nucleases—but don't cut the double helix and instead chemically alter single bases with deaminase enzymes such as TadA and ADAR.
—Jon Cohen, Science | AAAS, 25 Oct. 2017
Sharon Begley, STAT, 8 July 2020
Crucially, the mutations that had broken these genes could in principle be fixed with an adenine deaminase that worked on DNA.
—The Economist, 26 Oct. 2017
The enzyme needed is an adenine deaminase that works on DNA.
—The Economist, 26 Oct. 2017
Ramus was born with adenosine deaminase deficiency (ADA), a condition also known as bubble boy disease that affects the immune system.
—Paul A. Smith, Milwaukee Journal Sentinel, 27 Oct. 2017
Creating this second base editor was harder than the first because an equivalent to the cytidine deaminase used by Dr Liu, which would be needed to pull it off, does not exist in nature.
—The Economist, 26 Oct. 2017
Getting to the point of mutations Base editors borrow from CRISPR's components—guide RNAs (gRNAs) and Cas9 or other nucleases—but don't cut the double helix and instead chemically alter single bases with deaminase enzymes such as TadA and ADAR.
—Jon Cohen, Science | AAAS, 25 Oct. 2017
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Cite this Entry
“Deaminase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/deaminase. Accessed 17 Apr. 2024.
Copy CitationMedical Definition
deaminase
noun
de·am·i·nase
(ˈ)dē-ˈam-ə-ˌnās, -ˌnāz
variants
also desaminase
: an enzyme that hydrolyzes amino compounds (as amino acids) with removal of the amino group
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