chlor·​prom·​a·​zine | \ klȯr-ˈprä-mə-ˌzēn How to pronounce chlorpromazine (audio) \

Definition of chlorpromazine

: a phenothiazine C17H19ClN2S used chiefly as a tranquilizer especially in the form of its hydrochloride to control the symptoms of psychotic disorders (such as schizophrenia)

Examples of chlorpromazine in a Sentence

Recent Examples on the Web In the early 1950s, psychiatrists began treating schizophrenia with a new drug called chlorpromazine. Carl Zimmer, New York Times, "Old Drugs May Find a New Purpose: Fighting the Coronavirus," 30 Apr. 2020 Research suggests that chlorpromazine is the most likely to cause seizures among typical antipsychotics while clozapine is most likely among atypicals. Kimberly Truong, SELF, "11 Side Effects of Antipsychotics You Should Know About," 7 Dec. 2018 First-generation antipsychotics include chlorpromazine, haloperidol, perphenazine, and fluphenazine, the NIMH says. Korin Miller, SELF, "5 Bipolar Disorder Treatments You Should Know About," 30 Nov. 2018 By 1960, doctors had the first drug that could effectively blunt psychosis — chlorpromazine, brand name Thorazine — giving tens of thousands of residents a chance to live independently. Benedict Carey, New York Times, "Trump Wants More Asylums — and Some Psychiatrists Agree," 5 Mar. 2018 Those doctors offered an acid reducer for his stomach and more chlorpromazine. Lisa Sanders, M.d., New York Times, "Why Couldn’t This Man Stop Hiccupping?," 20 July 2017 Looking back, the purely unexpected discovery of lithium, chlorpromazine (the first antipsychotic drug) and several antidepressants around the 1950s promised rapid therapeutic progress. Dr. Claes Wahlestedt, miamiherald, "In treating mental illness, drugs are critical. Yet few are in the pipeline.," 6 June 2017 And last year, scientists working with mouse brain cells found that the anti-malaria drug quinacrine and the anti-psychotic drug chlorpromazine interfered with the ability of prions to cause normal brain protein to misfold. Mark Johnson, Milwaukee Journal Sentinel, "In tracking a lethal family of diseases that threatens humans and animals, scientists have become the hunters," 6 July 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'chlorpromazine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of chlorpromazine

1952, in the meaning defined above

History and Etymology for chlorpromazine

chlor- + propyl + methyl + azine

Keep scrolling for more

Learn More about chlorpromazine

Time Traveler for chlorpromazine

Time Traveler

The first known use of chlorpromazine was in 1952

See more words from the same year

Statistics for chlorpromazine

Last Updated

12 May 2020

Cite this Entry

“Chlorpromazine.” Dictionary, Merriam-Webster, Accessed 7 Jul. 2020.

Keep scrolling for more

More Definitions for chlorpromazine


chlor·​prom·​a·​zine | \ klōr-ˈpräm-ə-ˌzēn, klȯr- How to pronounce chlorpromazine (audio) \

Medical Definition of chlorpromazine

: a phenothiazine derivative that has antipsychotic, sedative, and antiemetic properties and is used in the form of its hydrochloride C17H19ClN2S·HCl especially to manage the symptoms of psychotic disorders (as schizophrenia) — see largactil, thorazine

More from Merriam-Webster on chlorpromazine Encyclopedia article about chlorpromazine

Comments on chlorpromazine

What made you want to look up chlorpromazine? Please tell us where you read or heard it (including the quote, if possible).


See Definitions and Examples »

Get Word of the Day daily email!

Test Your Vocabulary

A More Exception(al) Quiz

  • hot dog  hot dog  hot dog  hot dog cat
  • Which of the following words is not a synonym for ‘a young person’?
Spell It

Can you spell these 10 commonly misspelled words?

Syn City

Test Your Knowledge - and learn some interesting things along the way.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!