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Synonyms and Antonyms of operate

  1. 1 to control the mechanical operation of <do not operate heavy machinery, including cars, after taking this medication> Synonyms handle, run, work Related Words use; maneuver, manipulate, ply, wield; command, control, direct, drive, guide, pilot, steer

  2. 2 to look after and make decisions about <it takes years to learn how to operate that kind of business so that it makes money> Synonyms administer, administrate, carry on, control, direct, govern, guide, handle, keep, manage, conduct, overlook, oversee, preside (over), regulate, run, steward, superintend, supervise, tendRelated Words care (for), mind, watch; lead, pilot, steer; guard, protect, safeguard; micromanage, stage-manage; codirect, comanage

  3. 3 to produce a desired effect <the medicine will take an hour or so to operate the first time you use it> Synonyms act, perform, take, workRelated Words behave, react, respond; affect, influence, sway; pan out, redound, resultNear Antonyms backfire; fizzle

  4. 4 to put into action or service <wouldn't dream of operating a vehicle under the influence of alcohol> Synonyms apply, employ, exercise, exploit, harness, use, utilizeRelated Words handle, manipulate, wield; direct, run, work; cannibalize, recycle, reuseNear Antonyms ignore, neglect; misapply, misuse

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mysterious, holy, or spiritual

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