Synonyms of first-line

first-line

adjective

ˈfərst-ˈlīn 

as in selected

singled out from a number or group as more to one's liking

surgery is usually not considered a first-line treatment for this type of cancer

Synonyms & Similar Words

• selected
• select
• favorite
• preferred
• favored
• chosen
• elect
• choice
• of choice
• handpicked
• picked
• fashionable
• cherry-picked
• exclusive
• screened
• weeded (out)
• picked over
• winnowed (out)
• culled

Antonyms & Near Antonyms

• average
• common
• ordinary
• commonplace
• run-of-the-mill

Example Sentences

Recent Examples of first-line

This system was able to categorize ear wax samples with 94 percent accuracy, with the researchers saying this could lead to a first-line screening tool for early-onset Parkinson's. —Alyce Collins, MSNBC Newsweek, 24 June 2025

Here’s Why You Might Prior guidelines have recommended trying lifestyle interventions before beginning medication, but this new guidance recommends considering these medications as a first-line treatment option for eligible patients. —Lauryn Higgins, Flow Space, 20 June 2025

No matter how risky Boeser’s next contract is likely to be, the minutes that he’s consistently handled in a first-line role and his overall reliability as a top-line calibre player will be difficult for Vancouver to replace. —Thomas Drance, New York Times, 17 June 2025

For the most part, standard treatments typically focus on topical ointments that include: Metronidazole and azelaic acid are first-line topical medications that help reduce redness and inflammation. —Lauryn Higgins, Flow Space, 12 June 2025