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Medical Dictionary

von Willebrand disease

noun von Wil·le·brand disease \-ˌbränt-\

Medical Definition of von Willebrand disease

  1. :  a genetic blood disorder marked by prolonged, excessive, or abnormal bleeding that commonly results in recurrent nosebleeds, heavy menstrual flow, and bleeding from the gums, is caused by deficient or defective von Willebrand factor, and typically occurs in a mild form that is less serious than hemophilia Von Willebrand disease is inherited chiefly as an autosomal dominant trait in which only one parent must pass on a copy of the defective gene on a chromosome other than a sex chromosome.

Variants of von willebrand disease


von Willebrand's disease

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a sculptured or ornamented band

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