virulent

adjective

vir·​u·​lent ˈvir-ə-lənt 

ˈvir-yə-

1

a

: marked by a rapid, severe, and destructive course

a virulent infection

b

: able to overcome bodily defensive mechanisms : markedly pathogenic

virulent bacteria

2

: extremely poisonous or venomous

3

: full of malice : malignant

virulent racists

4

: objectionably harsh or strong

virulent criticism

virulently adverb

Synonyms

• malicious
• vicious
• cruel
• hateful
• nasty

Examples of virulent in a Sentence

The country seemed to be returning to the virulent nationalism of its past.

the virulent look on her face warned me that she was about to say something unkind

Recent Examples on the Web

Mounting fear within the Jewish and Conservative communities of New York is that Mamdani’s furtive stance of justice for Palestine and divestment from Israel is stoking the flame of more virulent Anti-Semitism to come. —Alexandra Bregman, Forbes.com, 1 July 2025

It's been 28 years since the rage virus — a virulent, bloodborne infection that sends its hosts into extreme, uncontrollable rage and states of undead decay — escaped a lab and decimated nearly all of the United Kingdom, now under rigid quarantine. —EW.com, 20 June 2025

Studies have shown that microorganisms can become more virulent and form stronger, thicker biofilms in space. —Jasmine Laws, MSNBC Newsweek, 20 May 2025

Besides condemnations cloaked in virulent antisemitism and anti-Zionism, many questioned Israel’s open war against Iran and its implications for President Donald Trump’s commitment to restore safety and security around the world. —Dr. Robert G. Rabil, Sun Sentinel, 23 June 2025

Word History

Etymology

Middle English, "discharging watery pus, purulent," borrowed from Latin vīrulentus "full of poison, venomous," from vīrus "venom, poisonous fluid" + -ulentus "having in quantity, full of" — more at virus

First Known Use

14th century, in the meaning defined at sense 1a

Phrases Containing virulent

• hyper-virulent

Rhymes for virulent

• avirulent

Kids Definition

virulent

adjective

vir·​u·​lent ˈvir-(y)ə-lənt 

1

a

: marked by a rapid, severe, and often deadly course

a virulent infection

b

: able to overcome or break down the defenses of the body

a virulent germ

2

: extremely poisonous : noxious

3

: full of hate : spiteful

virulently adverb

Medical Definition

virulent

adjective

vir·​u·​lent -lənt 

1

a

: marked by a rapid, severe, and malignant course

a virulent infection

b

: able to overcome bodily defense mechanisms

a virulent pathogen

2

: extremely poisonous or venomous : noxious