Medical Definition of titration
: a method or the process of determining the concentration of a dissolved substance in terms of the smallest amount of a reagent of known concentration required to bring about a given effect in reaction with a known volume of the test solution; especially : the analytical process of successively adding from a burette measured amounts of a reagent to a known volume of a sample in solution or a known weight of a sample until a desired end point (as a color change) is reached
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