testosterone

noun

tes·​tos·​ter·​one te-ˈstä-stə-ˌrōn How to pronounce testosterone (audio)
1
: a hormone that is a hydroxy steroid ketone C19H28O2 produced especially by the testes or made synthetically and that is responsible for inducing and maintaining male secondary sex characters
2
: qualities (such as brawn and aggressiveness) usually associated with males : manliness

Examples of testosterone in a Sentence

Recent Examples on the Web
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The following day, the NCAA's board voted to align its policy with the president's order, deciding women's teams would not be open to athletes who were recorded as male at birth or taking testosterone therapy. Joe Walsh, CBS News, 1 July 2026 Just a few years ago, trans-rights activists were arguing that the swimmer Lia Thomas, who transitioned from male to female while in college, could fairly compete against women simply by suppressing her testosterone. Helen Lewis, The Atlantic, 1 July 2026 For decades, medical guidelines advised against all hormones – from estrogen to testosterone – for all breast cancer survivors. Laura Trujillo, USA Today, 30 June 2026 Studies have shown testosterone produced during male puberty does lead to more muscle mass, larger hearts and lungs, greater body height and longer limbs on average for boys and men, according to the American College of Sports Medicine. Devin Dwyer, ABC News, 30 June 2026 See All Example Sentences for testosterone

Word History

Etymology

borrowed from German Testosteron, from Latin testēs testes + German -o- -o- + -steron -sterone

Note: The name was introduced by the Hungarian pharmacologists Karoly Gyula David (1905-45) and János Freud (1901-48), the Dutch endocrinologist Elisabeth Dingemanse (1886-1952), and the German-born Dutch physician and pharmacologist Ernst Laqueur (1880-1947) (all affiliated with the Pharmaco-Therapeutic Laboratory of the University of Amsterdam) in "Über krystallinisches männliches Hormon aus Hoden (Testosteron), wirksamer als aus Harn oder aus Cholesterin bereitetes Androsteron," Zeitschrift für physiologische Chemie, Band 233 (1935), pp. 281-83.

First Known Use

1935, in the meaning defined at sense 1

Time Traveler
The first known use of testosterone was in 1935

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Cite this Entry

“Testosterone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/testosterone. Accessed 5 Jul. 2026.

Kids Definition

testosterone

noun
tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn How to pronounce testosterone (audio)
: a male hormone produced by the testes that causes the development of the male reproductive system and secondary sex characteristics

Medical Definition

testosterone

noun
tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn How to pronounce testosterone (audio)
: a male hormone that is a crystalline hydroxy steroid ketone C19H28O2 produced primarily by the testes or made synthetically and that is the main androgen responsible for inducing and maintaining male secondary sex characteristics see androgel, axiron

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