testosterone

noun

tes·​tos·​ter·​one te-ˈstä-stə-ˌrōn 

1

: a hormone that is a hydroxy steroid ketone C₁₉H₂₈O₂ produced especially by the testes or made synthetically and that is responsible for inducing and maintaining male secondary sex characters

2

: qualities (such as brawn and aggressiveness) usually associated with males : manliness

Examples of testosterone in a Sentence

Recent Examples on the Web

There are a lot of clinics now that are pushing TRT, and people are trying to optimize their testosterone. — Teresa Maalouf, Verywell Health, 14 Aug. 2026

Paramount appears to be, as a recent THR report detailed, finally turning its attention to women after so many years relying on the work of Taylor Sheridan and his abundant testosterone. — Mikey O'Connell, HollywoodReporter, 13 Aug. 2026

Unfortunately, this happens quite often due to my complete lack of mobility as a perimeter defender, a weakness that appears to have nothing to do with the estrogen or testosterone levels of my opponent. — Julia Poe, Chicago Tribune, 13 Aug. 2026

Experts say the situation is highlighting a bigger issue at hand than testosterone deficiency − an obsession with and major misunderstanding about masculinity. — Sara Moniuszko, USA Today, 13 Aug. 2026

Word History

Etymology

borrowed from German Testosteron, from Latin testēs testes + German -o- -o- + -steron -sterone

Note: The name was introduced by the Hungarian pharmacologists Karoly Gyula David (1905-45) and János Freud (1901-48), the Dutch endocrinologist Elisabeth Dingemanse (1886-1952), and the German-born Dutch physician and pharmacologist Ernst Laqueur (1880-1947) (all affiliated with the Pharmaco-Therapeutic Laboratory of the University of Amsterdam) in "Über krystallinisches männliches Hormon aus Hoden (Testosteron), wirksamer als aus Harn oder aus Cholesterin bereitetes Androsteron," Zeitschrift für physiologische Chemie, Band 233 (1935), pp. 281-83.

First Known Use

1935, in the meaning defined at sense 1

Rhymes for testosterone

• aldosterone
• anticyclone
• hydrocodone
• progesterone
• acetone
• anglophone
• baritone
• bourguignon
• buspirone
• chaperon
• chaperone
• cobblestone

Kids Definition

testosterone

noun

tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn 

: a male hormone produced by the testes that causes the development of the male reproductive system and secondary sex characteristics

Medical Definition

testosterone

noun

tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn 

: a male hormone that is a crystalline hydroxy steroid ketone C₁₉H₂₈O₂ produced primarily by the testes or made synthetically and that is the main androgen responsible for inducing and maintaining male secondary sex characteristics see androgel, axiron