testosterone

noun

tes·​tos·​ter·​one te-ˈstä-stə-ˌrōn 

1

: a hormone that is a hydroxy steroid ketone C₁₉H₂₈O₂ produced especially by the testes or made synthetically and that is responsible for inducing and maintaining male secondary sex characters

2

: qualities (such as brawn and aggressiveness) usually associated with males : manliness

Examples of testosterone in a Sentence

Recent Examples on the Web

Studies have linked phthalates with reproductive problems, such as genital malformations and undescended testes in baby boys and lower sperm counts and testosterone levels in adult males. — Sandee Lamotte, CNN Money, 28 Aug. 2026

Some undergo cosmetic procedures and reportedly inject their bodies with peptides, testosterone, and other substances that enhance their physiques. — José Criales-Unzueta, Vanity Fair, 27 Aug. 2026

The research proposes that flavonoids and saponins in legumes may have greater effects involving testosterone, while compounds in cruciferous vegetables could interact more strongly with estrogen and progesterone pathways. — Paul McClure 23, New Atlas, 23 Aug. 2026

Cortisol, for example, can change throughout the day, testosterone can fluctuate from day to day, and estrogen and progesterone shift wildly over the course of the menstrual cycle. — Cathy Cassata, HEALTH, 21 Aug. 2026

Word History

Etymology

borrowed from German Testosteron, from Latin testēs testes + German -o- -o- + -steron -sterone

Note: The name was introduced by the Hungarian pharmacologists Karoly Gyula David (1905-45) and János Freud (1901-48), the Dutch endocrinologist Elisabeth Dingemanse (1886-1952), and the German-born Dutch physician and pharmacologist Ernst Laqueur (1880-1947) (all affiliated with the Pharmaco-Therapeutic Laboratory of the University of Amsterdam) in "Über krystallinisches männliches Hormon aus Hoden (Testosteron), wirksamer als aus Harn oder aus Cholesterin bereitetes Androsteron," Zeitschrift für physiologische Chemie, Band 233 (1935), pp. 281-83.

First Known Use

1935, in the meaning defined at sense 1

Rhymes for testosterone

• aldosterone
• anticyclone
• hydrocodone
• progesterone
• acetone
• anglophone
• baritone
• bourguignon
• buspirone
• chaperon
• chaperone
• cobblestone

Kids Definition

testosterone

noun

tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn 

: a male hormone produced by the testes that causes the development of the male reproductive system and secondary sex characteristics

Medical Definition

testosterone

noun

tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn 

: a male hormone that is a crystalline hydroxy steroid ketone C₁₉H₂₈O₂ produced primarily by the testes or made synthetically and that is the main androgen responsible for inducing and maintaining male secondary sex characteristics see androgel, axiron