Medical Definition of systemic circulation
: the passage of arterial blood from the left atrium of the heart through the left ventricle, the systemic arteries, and the capillaries to the organs and tissues that receive much of its oxygen in exchange for carbon dioxide and the return of the carbon-dioxide carrying blood via the systemic veins to enter the right atrium of the heart and to participate in the pulmonary circulation
Seen and Heard
What made you want to look up systemic circulation? Please tell us where you read or heard it (including the quote, if possible).