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signature
1
: a feature in the appearance or qualities of a natural object formerly held to indicate its utility in medicine either because of a fancied resemblance to a body part (as a heart-shaped leaf indicating utility in heart disease) or because of a presumed relation to some phase of a disease (as the prickly nature of thistle indicating utility in case of a stitch in the side)
2
: the part of a medical prescription which contains the directions to the patient
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