Medical Dictionary

Sandhoff's disease

noun Sand·hoff's disease \ˈsand-ˌhfs-\

Medical Definition of SANDHOFF'S DISEASE

:  a hereditary disorder of lipid metabolism that is closely related to or a variant of Tay-Sachs disease, that typically affects individuals of non-Jewish ancestry, and that is characterized by great reduction in or absence of both hexosaminidase A and hexosaminidase B

Biographical Note for SANDHOFF'S DISEASE

Sandhoff, K., An·dreae \än-ˈdrā-e\ , U., and Jatz·ke·witz \ˈyäts-kə-ˌvits\ H. German medical scientists. Sandhoff, Andreae, and Jatzkewitz jointly published a description of a variant form of Tay-Sachs disease in 1968. They based their report on three typical cases of Tay-Sachs, one exceptional case, and seven controls.


Sand·hoff's disease or Sand·hoff disease \-ˌhf-\


How to use a word that (literally) drives some people nuts.
Test your vocab with our fun, fast game
Ailurophobia, and 9 other unusual fears