1
: a crystalline base C5H4N4 that is the parent of compounds of the uric-acid group
2
: a derivative of purine
especially : a base (such as adenine or guanine) that is a constituent of DNA or RNA

Examples of purine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Laing also cautioned that sardines contain purines, which may cause a buildup of uric acid and worsen symptoms like joint pain and swelling for people with gout. Stephanie Brown, Verywell Health, 24 Apr. 2026 Ryugu contained roughly equal amounts of purines and pyrimidines, while Murchison was richer in purine nucleobases. Devika Rao, TheWeek, 24 Mar. 2026 The chemistry leading to their formation will necessarily be somewhat distinct, so the researchers pooled the purines and pyrimidines and compared their concentrations across multiple asteroids. ArsTechnica, 21 Mar. 2026 Ryugu contains roughly comparable amounts of the nucleobases, adenine and guanine (known as purines), to cytosine, thymine, and uracil (pyrimidines). Robert Lea, Space.com, 17 Mar. 2026 See All Example Sentences for purine

Word History

Etymology

German Purin, from Latin purus pure + New Latin uricus uric (from English uric) + German -in -ine entry 2

First Known Use

1898, in the meaning defined at sense 1

Time Traveler
The first known use of purine was in 1898

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Cite this Entry

“Purine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/purine. Accessed 10 Jul. 2026.

Kids Definition

: any of a group of bases including several (as adenine or guanine) that are important parts of DNA and RNA

Medical Definition

1
: a crystalline base C5H4N4 that is the parent of compounds of the uric-acid group
2
: a derivative of purine
especially : a base (as adenine or guanine) that is a constituent of DNA or RNA

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