Medical Definition of polyomavirus
1 capitalized : a genus of double-stranded DNA viruses (family Polyomaviridae) that contain a single molecule of DNA, have a capsid composed of 72 capsomers, and induce tumors usually in specific mammals and that include simian virus 40 and the causative agent of progressive multifocal leukoencephalopathy
2: any of the genus Polyomavirus of double-stranded DNA viruses
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