plaque

noun

ˈplak 

1

a

: an ornamental brooch

especially : the badge of an honorary order

b

: a flat thin piece (as of metal) used for decoration

c

: a commemorative or identifying inscribed tablet

2

a

: a localized abnormal patch on a body part or surface

b

: a sticky usually colorless film on teeth that is formed by and harbors bacteria

c

: an atherosclerotic lesion

d

: a histopathologic lesion of brain tissue that is characteristic of Alzheimer's disease and consists of a dense proteinaceous core composed primarily of beta-amyloid that is often surrounded and infiltrated by a cluster of degenerating axons and dendrites

3

: a clear area in a bacterial culture produced by viral destruction of cells

Examples of plaque in a Sentence

A bronze plaque marked the city's oldest building.

They gave him a plaque in honor of his 30 years of service.

Brushing your teeth prevents the buildup of plaque.

The scientists are studying the way the plaques form.

Recent Examples on the Web

Additionally, an Apolipoprotein B-100 (Apo B) test, which measures the amount of plaque-forming protein in your blood, offers a more accurate picture of heart disease than a standard cholesterol test. — Helen Carefoot, Flow Space, 10 Sep. 2026

Alvarez and his wife, Adda, have made memorial plaques for animals of all types, from dogs, cats and horses to bees, wolves and crawfish. — Yvonne Villasenor, Los Angeles Times, 10 Sep. 2026

Removing excess cholesterol helps prevent arterial plaque buildup, which can restrict or block blood flow to vital organs such as the heart or brain. — Colleen Doherty, Verywell Health, 8 Sep. 2026

Behind the plaque, in a large irregular recess set with a metal grille, there was an inscription with names. — Literary Hub, 8 Sep. 2026

Word History

Etymology

French, from Middle French, metal sheet, from plaquer to plate, from Middle Dutch placken to piece, patch; akin to Middle Dutch placke piece, Middle High German placke patch

First Known Use

1845, in the meaning defined at sense 1a

Phrases Containing plaque

• anti-plaque

Rhymes for plaque

• ack
• brack
• clack
• crack
• dak
• flack
• flak
• hack
• jack
• knack
• lac
• lack

Kids Definition

plaque

noun

ˈplak 

1

: an ornamental pin

especially : an honorary badge

2

: a flat thin piece (as of metal) used for decoration or inscribed as a memorial or marker

3

: a sticky usually colorless film on teeth that is formed by and contains bacteria

Medical Definition

plaque

noun

variants also placque

ˈplak 

1

a

: a localized abnormal patch on a body part or surface and especially on the skin

psoriatic plaque

b

: a sticky usually colorless film on teeth that is formed by and harbors bacteria

c

: an atherosclerotic lesion

d

: a histopathologic lesion of brain tissue that is characteristic of Alzheimer's disease and consists of a dense proteinaceous core composed primarily of beta-amyloid that is often surrounded and infiltrated by a cluster of degenerating axons and dendrites

called also senile plaque

2

: a visibly distinct and especially a clear or opaque area in a bacterial culture produced by damage to or destruction of cells by a virus