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Medical Dictionary

Philadelphia chromosome

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noun Phil·a·del·phia chromosome \ˌfil-ə-ˈdel-fē-ə-\

Medical Definition of Philadelphia chromosome

  1. :  an abnormally short chromosome 22 that is found in the hematopoietic cells of persons affected with chronic myelogenous leukemia and lacks the major part of its long arm which has usually undergone translocation to chromosome 9




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