perforation

per·fo·ra·tion

noun \ˌpər-fə-ˈrā-shən\

Definition of PERFORATION

1

: the act or process of perforating; specifically : the penetration of a body part through accident or disease <spontaneous perforation of the sigmoid colon in the presence of diverticulosis—Journal of the American Medical Association>

2

a : a rupture in a body part caused especially by accident or disease b : a natural opening in an organ or body part