Medical Dictionary

perforation

noun per·fo·ra·tion \ˌpər-fə-ˈrā-shən\

Medical Definition of PERFORATION

1
:  the act or process of perforating; specifically :  the penetration of a body part through accident or disease <spontaneous perforation of the sigmoid colon in the presence of diverticulosis—Journal of the American Medical Association>
2
a :  a rupture in a body part caused especially by accident or disease b :  a natural opening in an organ or body part

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