paroxysmal nocturnal hemoglobinuria


paroxysmal nocturnal hemoglobinuria

noun

Definition of PAROXYSMAL NOCTURNAL HEMOGLOBINURIA

: a form of hemolytic anemia that is characterized by an abnormally strong response to the action of complement, by acute episodes of hemolysis especially at night with hemoglobinuria noted upon urination after awakening, venous occlusion, and often leukopenia and thrombocytopenia—abbreviation PNH

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