: a tumor suppressor gene that in an inactivated form tends to be associated with a high risk of certain cancers
Examples of p53 in a Sentence
Recent Examples on the Web
Studies on the closely related SARS-CoV have implicated viral proteins in the possible degradation of p53 and pRB, which are critical oncosuppressors.
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Carolyn Barber, Fortune, 23 Nov. 2023
Another obvious example would be the p53 gene, which is very strongly associated with cancer suppression.
—Bill Gifford, Scientific American, 31 July 2023
In mammals, p53 plays a crucial role in preventing mutated cells from turning into tumors.
—Rachel Nuwer, Scientific American, 8 Sep. 2022
This wasn’t the first time that researchers noticed the p53, now more commonly called TP53, gene.
—Anna Funk, Discover Magazine, 17 May 2021
The same is true for p53.
—Max G. Levy, Wired, 24 May 2021
These mice lack a particular protein or biological function, such as the ability to produce Carboxypeptidase E, a type of protein building block whose absence results in mice with obesity, or to produce the p53 protein, which leads to mice much more likely to develop any of several types of cancer.
—David H. Freedman, Discover Magazine, 7 Feb. 2020
By 1990, researchers had identified the gene in question: One called p53 that, among other roles in the body’s cells, helps suppress tumors.
—Anna Funk, Discover Magazine, 17 May 2021
This form of cancer is one where there doesn't seem to be a somatic cell mutation of p53 itself.
—Razib Khan, Discover Magazine, 17 Oct. 2013
Carolyn Barber, Fortune, 23 Nov. 2023
Another obvious example would be the p53 gene, which is very strongly associated with cancer suppression.
—Bill Gifford, Scientific American, 31 July 2023
In mammals, p53 plays a crucial role in preventing mutated cells from turning into tumors.
—Rachel Nuwer, Scientific American, 8 Sep. 2022
This wasn’t the first time that researchers noticed the p53, now more commonly called TP53, gene.
—Anna Funk, Discover Magazine, 17 May 2021
The same is true for p53.
—Max G. Levy, Wired, 24 May 2021
These mice lack a particular protein or biological function, such as the ability to produce Carboxypeptidase E, a type of protein building block whose absence results in mice with obesity, or to produce the p53 protein, which leads to mice much more likely to develop any of several types of cancer.
—David H. Freedman, Discover Magazine, 7 Feb. 2020
By 1990, researchers had identified the gene in question: One called p53 that, among other roles in the body’s cells, helps suppress tumors.
—Anna Funk, Discover Magazine, 17 May 2021
This form of cancer is one where there doesn't seem to be a somatic cell mutation of p53 itself.
—Razib Khan, Discover Magazine, 17 Oct. 2013
These examples are programmatically compiled from various online sources to illustrate current usage of the word 'p53.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
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“P53.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/p53. Accessed 24 Apr. 2024.
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p53
noun
: a tumor suppressor gene that in a defective form tends to be associated with a high risk of certain cancers (as of the colon, lung, and breast)
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