Medical Definition of orbital fissure
: either of two openings transmitting nerves and blood vessels to or from the orbit:a: one situated superiorly between the greater wing and the lesser wing of the sphenoid bone—called also superior orbital fissure, supraorbital fissureb: one situated inferiorly between the greater wing of the sphenoid bone and the maxilla—called also inferior orbital fissure, infraorbital fissure, sphenomaxillary fissure
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