: any of various colorless proteins that in combination with retinal or a related prosthetic group form a visual pigment (such as rhodopsin) in a reaction reversible by light

Examples of opsin in a Sentence

Recent Examples on the Web
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This gene is different from the opsin genes that are found in their eyes. Laura Baisas, Popular Science, 23 Aug. 2023 In a 2018 study, Schweikert and colleagues found the fish sensed light with their skin using a protein called opsin. Will Sullivan, Smithsonian Magazine, 24 Aug. 2023 In an outpatient procedure, clinicians would inject an opsin gene into the nerve through a natural opening in the skull above the upper jaw. New Atlas, 16 Jan. 2026 Instead of using amino acids—found in other animal opsins—ASO-II opsins employ chloride ions. Maria Mocerino, Interesting Engineering, 7 Sep. 2025 See All Example Sentences for opsin

Word History

Etymology

from -opsin (in porphyropsin and rhodopsin)

Note: Term introduced by the American physiologist George Wald (1906-97) in "The Chemistry of Rod Vision," Science, vol. 113, issue 2933, March 16, 1951, p. 287: "Rhodopsin and porphyropsin are carotenoid-proteins—proteins bearing carotenoid prosthetic groups to which they owe their color and sensitivity to light. Each of these pigments possesses a single type of prosthetic group. The protein probably varies from one animal to another; it may be called opsin, and named for the animal of origin."

First Known Use

1951, in the meaning defined above

Time Traveler
The first known use of opsin was in 1951

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Cite this Entry

“Opsin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/opsin. Accessed 7 Jul. 2026.

Medical Definition

: any of various colorless proteins that in combination with retinal or a related prosthetic group form a visual pigment (as rhodopsin) in a reaction which is reversed by light

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