Medical Definition of migraine
1: a condition that is marked by recurrent usually unilateral severe headache often accompanied by nausea and vomiting and followed by sleep, that tends to occur in more than one member of a family, and that is of uncertain origin though attacks appear to be precipitated by dilatation of intracranial blood vessels
2: an episode or attack of migraine <suffers from migraines>—called also sick headache
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