Medical Definition of manipulate
1: to treat or operate with the hands or by mechanical means especially in a skillful manner <manipulate the fragments of a broken bone into correct position>
2a: to manage or utilize skillfullyb: to control or play upon by artful, unfair, or insidious means especially to one's own advantage
Seen and Heard
What made you want to look up manipulate? Please tell us where you read or heard it (including the quote, if possible).