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Medical Dictionary


noun mac·ro·lide \ˈmak-rə-ˌlīd\

Medical Definition of macrolide

  1. :  any of several antibiotics (as erythromycin or clarithromycin) that contain a usually 14- to 16-membered macrocyclic lactone ring, inhibit bacterial RNA-dependent protein synthesis, and are effective especially against gram-positive bacteria (such as staphylococci and streptococci)

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