ligand

noun

li·​gand ˈli-gənd How to pronounce ligand (audio) ˈlī- How to pronounce ligand (audio)
: a group, ion, or molecule coordinated to a central atom or molecule in a complex

Examples of ligand in a Sentence

Recent Examples on the Web At the intersection, the ligand between society and art is the medium of photography. Caterina De Biasio, Vogue, 20 Mar. 2024 These opioid receptors when stimulated and/or inhibited by the body's natural ligands have been known to be involved in the body's itch circuitry. Sacramento Bee, 5 Feb. 2024 The palladium can link up with four ligands at a time, which can link up with other palladium-ligand groups to form the cage-like structures; the more palladium atoms in the mix, the bigger the cages. Bill Andrews, Discover Magazine, 18 July 2018 The palladium can link up with four ligands at a time, which can link up with other palladium-ligand groups to form the cage-like structures; the more palladium atoms in the mix, the bigger the cages. Bill Andrews, Discover Magazine, 18 July 2018 These drugs, especially intravenous zoledronic acid (and the antibody to RANK ligand, denosumab), have been game-changers in patients with breast and other cancers that spread to bone. Dr. Keith Roach, oregonlive, 9 Aug. 2022 As a transmembrane protein, STING has two main domains: a transmembrane domain and cytoplasmic ligand-binding domain. William A. Haseltine, Forbes, 21 Apr. 2022 Electron density maps revealed that the remdesivir metabolite GS-441524 was the only ligand that showed binding in the crystal structures. William A. Haseltine, Forbes, 4 June 2021 One common example of a ligand is found in siderophores, chemical compounds that bacteria secrete to break down iron particles. Emily Underwood, Smithsonian Magazine, 3 Jan. 2020

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'ligand.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

Latin ligandus, gerundive of ligare

First Known Use

1949, in the meaning defined above

Time Traveler
The first known use of ligand was in 1949

Dictionary Entries Near ligand

Cite this Entry

“Ligand.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ligand. Accessed 18 Apr. 2024.

Medical Definition

ligand

noun
li·​gand ˈlig-ənd How to pronounce ligand (audio) ˈlīg- How to pronounce ligand (audio)
: a group, ion, or molecule coordinated to a central atom or molecule in a complex
liganded adjective

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